Description: Insulin secretion from pancreatic β-cells plays a central role in the control of body metabolism. Dysfunction and/or loss of β-cells can result in the release of insufficient amounts of insulin and in the development of different forms of diabetes mellitus. Β-cell dysfunction is linked to gene expression changes but the precise mechanisms underlying the phenomenon are still insufficiently understood. Recent studies from different laboratories including ours provided evidence that non-coding RNAs play an important role in the control of β-cell activities. The goal of the project that is supported by a grant from the Swiss National Science Foundation will be to determine the involvement of microRNAs and other newly discovered classes of non-coding RNAs in the regulation of β-cell functions and to evaluate their contribution in the appearance of diabetes mellitus.
Qualifications: The position requires a doctoral degree in Life Sciences or related disciplines. Candidates with experience in molecular biology and gene expression analysis will be preferred.
Starting: The position is open starting from April 2018 but later entry dates are possible. The initial contract is for one year and can be renewed until a maximum of five years.
Remarks: Applications, including a letter of motivation, CV and names of 2 referees with email addresses and phone numbers should be sent via e-mail to the address below.
Prof. Romano Regazzi, Department of Fundamental Neurosciences, Rue du Bugnon 9 CH-1005 Lausanne
Keywords: Non-coding RNAs/Pancreatic islet/Gene expression/DiabetesContinue reading